Confirmed Speakers/Awardees

PRESIDER: Richard Gallo, MD/PhD

 

3:30 PM-3:45 PM

#506, Predicting the long-term outcomes of biologics in psoriasis patients using machine learning

1. S. Emam¹, A. Du², P. Surmanowicz², S. Thomsen¹, R. Griener¹, R. Gniadecki²

¹University of Alberta, Edmonton, Alberta, Canada, ²Medicine, University of Alberta, Edmonton, Alberta, Canada

 

3:45 PM-4:00 PM

#476, Utilization and impact of immunotherapy in stage IV melanoma using the National Cancer Database

1. R. Conic^{1, 2}, R. Knackstedt², G. Damiani², B. Gastman²

¹University of Maryland, Baltimore, Maryland, United States, ²Cleveland Clinic, Cleveland, Ohio, United States

 

4:00 PM-4:15 PM

#130, Small non-coding RNAs interact with ERK2 and effect MAPK/ERK pathway

1. Z. Siprashvili¹, R. M. Shenoy¹, L. Elcavage¹, P. Khavari^{1, 2}

¹Dermatology, Stanford University, Stanford, California, United States, ²VA Palo Alto Healthcare System, Palo Alto, California, United States

 

4:15 PM-4:30 PM

#861, Intravenous gentamicin therapy for junctional epidermolysis bullosa patients harboring nonsense mutations

1. M. Hao¹, R. Antaya², J. Cogan¹, C. Hamilton², Y. Hou¹, A. Kwong¹, D. Woodley¹, M. Chen¹

¹University of Southern California, Los Angeles, California, United States, ²Yale School of Medicine, New Haven, Connecticut, United States

 

4:30 PM-4:45 PM

#361, Skin-induced IL-36 triggers plasma cell IgE class switching and allergic disease

1. G. J. Patrick¹, H. Liu¹, M. Alphonse¹, D. Dikeman¹, C. Youn¹, J. Otterson¹, Y. Wang¹, A. Ravipati¹, Q. Liu¹, E. Raymond², M. Ramanujam², N. Archer¹, L. S. Miller¹

¹Dermatology, Johns Hopkins School of Medicine, Baltimore, Maryland, United States, ²Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, Connecticut, United States

Presiders: Kurt Lu, MD and Peggy Myung, MD/PhD 

 

3:30 PM-3:45 PM 

#561,  Development and first-in-human characterization of a potent oral CCR4 antagonist for the treatment of atopic dermatitis 

1. L.E. Cheng, A.Jorapur, S. Jacobson, O.Talay, S. Miakicheva, D. Trujillo, N. Lee, J. Jankicevic, D. Wustrow, P. Kassner, W. Ho, D. Brockstedt 

RAPT Therapeutics, Inc., South San Francisco, California, United States 

 

3:45 PM -4:00 PM 

#327 , Staphylococcus epidermidis protease EcpA is a deleterious component of the skin microbiome in atopic dermatitis 

1. L. Cau1, 2, M. Williams1, A. Butcher1, T. Nakatsuji1, J. Cheng1, T. Hata1, J. Kavanaugh3, C. Mainzer2, B. Closs2, A. Horswill3, R. L. Gallo1

1Dermatology Department, University of California, San Diego, California, United States, 2R&D Department, SILAB, Brive, France, 3Immunology and Microbiology Department, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States 

 

4:00 PM-4:15 PM 

#717,  Enhanced molecular signatures in cutaneous lupus erythematosus patients support distinct pathogenic pathways in African American patients 

1. J. L. Zhu1, L. Tran2, F. Zheng2, J. James2, J. Guthridge2, B. F. Chong1

1Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, United States, 2Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States 

 

4:15 PM-4:30 PM 

#775,  Hyperactivation of sympathetic nerves drives melanocyte stem cell depletion 

1. B. Zhang1, S. Ma1, 2, 3, I. Rachman4, M. He1, 5, P. Baral6, S. Choi1, W. A. Gonçalves10, Y. Shwartz1, E. M. Fast1, 7,   Y. Hsu4, L. I. Zon1, 7, 8, A. Regev2, 8, 3, J. D. Buenrostro1, T. M. Cunha6, 9, I. M. Chiu6, D. Fisher4, Y. Hsu1

1Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, United States, 2Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States, 3Department of Biology and Koch Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States, 4Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital, Charlestown, Massachusetts, United States, 5Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States, 6Department of Immunology, Harvard Medical School, Boston, Massachusetts, United States, 7Division of Hematology/Oncology, Boston Children’s Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts, United States, 8Howard Hughes Medical Institute, Chevy Chase, Maryland, United States, 9Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil, 10Graduate Program in Cellular Biology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil 

 

4:30 PM-4:45 PM 

#030,  VGLL3, an orchestrator of female-biased autoimmunity, interfaces with the Hippo pathway to modulate genes involved in immunity and fibrosis 

1. A.C. Billi1, C. Zeng1, M. Gharaee-Kermani2, S. W. Stoll1, M. J. Wilson1, O. Plazyo1, X. Xing1, J. M. McCarthy1, L. C. Tsoi4, 5, J. Kahlenberg2, A. A. Dlugosz1, 3, J. E. Gudjonsson1

1Dermatology, University of Michigan, Ann Arbor, Michigan, United States, 2Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan, United States, 3Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States, 4Biostatistics, University of Michigan, Ann Arbor, Michigan, United States, 5Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States 

PRESIDER: Vladimir Botchkarev, MD/PhD & Marjana Tomic-Canic, PhD

 

4:00 PM – 4:15 PM

#225,  Desmoglein 1 deficiency in knockout mice impairs epidermal barrier formation and results in a psoriasis-like gene signature in E18.5 embryos 

1. Q. R. Roth-Carter1, L. Godsel1, J. L. Koetsier1, J. A. Broussard1, 6, H. E. Burks1, G. Fitz4, A. L. Huffine1, S. Amagai1, S. Lloyd3, J. Kweon3, L. C. Tsoi2, W. R. Swindell2, G. Urciuoli5, C. Missero5, X. Bao3, J. E. Gudjonsson2, K. J. Green1, 6

1Department of Pathology, Northwestern University, Chicago, Illinois, United States, 2Dermatology, University of Michigan, Ann Arbor, Michigan, United States, 3Molecular Biosciences, Northwestern University, Evanston, Illinois, United States, 4Vanderbilt, Nashville, Tennessee, United States, 5CEINGE, Naples, Italy, 6Dermatology, Northwestern, Chicago, Illinois, United States 

 

 4:15 PM – 4:30 PM

#169,  MrgprD-expressing neurons maintain cutaneous mast cell homeostasis 

1. S. Zhang1, T. Edwards1, J. Cohen1, T. Hirai1, N. Rittenhouse2, E. Schmitz2, B. McNeil3, Y. Yang1, H. R. Koerber4, T. Sumpter1, A. Poholek2, K. Albers4, D. Kaplan1

1Dermatology and Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States, 2Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States, 3Allergy & Immunology, Northwestern University, Chicago, Illinois, United States, 4Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States 

 

 4:30 PM – 4:45 PM

#434,  Association of skin response in erythema and sclerosis with survival in chronic graft-versus-host disease 

1. L.X. Baker1, M. Byrne2, P. Martin3, S. Lee3, H. Chen2, M. Jagasia2, E. Tkaczyk1

1Department of Veterans Affairs and Vanderbilt Dermatology Translational Research Clinic, Nashville, Tennessee, United States, 2Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, United States, 3Fred Hutchinson Cancer Research Center, Seattle, Washington, United States 

 

 4:45 PM – 5:00 PM

#829,  Single-cell approaches to uncover adipocyte precursor heterogeneity and differentiation mechanisms in the skin 

1. G. Rivera1, K. Kamimoto1, E. Butka1, 2, W. Kong2, 1, S. Morris1, 2

1Developmental Biology, Washington University in St. Louis, St. Louis, Missouri, United States, 2Genetics, Washington University in St. Louis, St. Louis, Missouri, United States 

 

 5:00 PM – 5:15 PM

#659,  Regulation of 3D genome organization by the STAG2 tumor suppressor in melanoma 

1. Z. Chu, B. Zheng

Dermatology, MGH, Harvard Med School, Boston, Massachusetts, United States